Medium and large drones cause significantly more damage than small drones. But they are also much slower and have much worse tracking.
The Vexor can field a theoretical maximum damage set of drones consisting of 2x Ogre II, 2x Hammerhead II and 1x Hobgoblin II. While this gives the theoretical maximum damage, I'm wondering if the Ogre II can actually apply significant damage on cruiser-sized targets. If they could not, then using all medium drones might be a better idea for cruiser fights.
I'm ignoring flight time for the moment, as this depends a lot on the distance of the drones and is something I can calculate with EFT/Pyfa. I'm mostly interested in the effect of tracking on attacking smaller drones, and I can't see a way to simulate that with either EFT or Pyfa.
What are the minimum target sizes for medium and small drones above which they can apply most of their damage effectively? How effective would large drones be against AB-fitted cruisers?