I usually play Dead Space on the hardest difficulty setting (except the "limited saves" mode), but it's been a while so I started up Dead Space 3 on the second hardest mode. While I die quickly, it's not all that hard.
So what all is the difference between the difficulty modes? How significant is each step up? Is it just that you pick up less ammo and necromorphs take/deal more damage (which I believe was how the first games work)? Does difficulty affect those all-too-precious resource drops?