Before you start your queue you can set up matchmaking settings. There you have Game Modes, Region and Language options.
Now I have set them all up to my liking, but I have a problem with regional setting. The game seems to save/remember all other settings I've selected except in which regions do I want to play. So every time I start the game, I have to pick regions all over again.
Is this some kind of bug, or is the game made that way? Is there a way to make the game remember my region settings too?