I'm playing in TVHM and just finished the first part of the Tiny Tina quest "You Are Cordially Invited: Party Prep" where you have to retrieve Sir Reginald from Madame von Bartlesby. I blasted her from a distance, using a sniper rifle from the Tundra Express map entry area, instead of dealing with her directly on Skittering Mound. Her body dropped at the foot of the mountain, and there was no loot at all. I was expecting some sort of legendary item, specifically the Baby Maker. Did I mess up by not killing her on Skittering Mound?
No. Drops in Borderlands 2 are almost always chance-based. In particular, legendary item drops usually only have about a 1 in 30 chance of actually dropping.