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In Deus-Ex, I'm trying to play a run wherein the main character is a cruel, merciless cyborg who cannot distinguish between friend and foe. Basically, everybody dies.

Things seemed to be going well in the first mission, where one of my comrades greeted me after I annihilated the enemy's leader and I proceeded to unload a 12 gauge into his lovable face, causing him to keel over and die. I stole his assault rifle and went down the stairs to my next friend, who told me what a great guy I was. I smiled and agreed and stabbed him 37 times in the chest. The only problem is that this didn't kill him; it caused him to get aggravated at me and shoot me with several poisonous darts as a form of comeuppance, rendering me quite dead.

Are there some comrades who simply won't die and who will endure whatever pains I put them through, or do I lack the necessary firepower to eliminate them at this point?

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Perhaps you need to try crushing them with furniture? – sjohnston Jan 4 '11 at 18:18
+1 for misanthropy. – LessPop_MoreFizz Jan 4 '11 at 18:21
A new contender for the title of Gaming's "that mass murderer", eh? ♪ – Grace Note Jan 4 '11 at 18:26
@LessPop I originally wanted to pop a quick joke on how it seems that everywhere I'll look on this site, I'll find a mass-murderer, but it seems that I am indeed surrounded. – Grace Note Jan 4 '11 at 18:33
If you're really serious about being 100% lethal, get ready to spend a lot of time chasing down rats and pigeons. Now if only I could find a way to swat the flies... – Feral Chimp Jan 5 '11 at 20:11
up vote 20 down vote accepted

There are definitely characters you can't kill, or that you can't kill until certain points in the plot. I'm not sure about all of them, but Paul springs to mind in the first mission. I've unloaded a great deal of ammo into him many a time, and he just keeps running around and eventually shoots me to death with a plasma rifle.

Your best bet is to save before you try to kill any main-plot characters, I suppose; hopefully that won't ruin the experience for ya.

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+1, I'm almost certain this is correct. Between many play-throughs and obsessive-compulsive experimentation I've tried both extremes, completely non-lethal and completely lethal. Neither seems possible: the game requires at least one character to die as a result of your actions (maybe two... I can't recall), and certain plot-essential characters are protected. – Feral Chimp Jan 5 '11 at 20:10
I won't name the character, but if it's the one I suspect, I've read that it is possible to save him/her - just really tricky to pull off. I certainly never managed it, so can't confirm it, alas. – Cyclops Mar 16 '11 at 0:31
@Cyclops There's a question on that: – Zommuter Sep 2 '13 at 13:10

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