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Throughout To the Moon, Eva and Neil mention that River had a certain condition that causes someone to answer questions literally (that's how I took it but it probably had another effect).

What condition are they referring to?

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1 Answer 1

up vote 9 down vote accepted

River has Asperger's syndrome, which is an autism spectrum disorder than can cause difficulties in social interaction.

This is evidenced by the doctor's recommendation that Johnny read some of the books written by Tony Attwood, a psychologist who has written several books on Asperger's syndrome.

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