What is the best/fastest way to acquire cracked red eye orbs? I'm level 150 and short of dueling other Brotherhood of Blood members I cannot find a way to acquire these. Dueling doesn't appear to be a very good method because it often takes over five minutes to land a duel.
There are several monsters that drop the orbs:
The one that has given me the best drop rate is the Fire Salamander.
Here's a video of someone farming the little Piglets in Majula.
Also, Titchy Gren (The Brotherhood of Blood guy) sells them for 10,000 souls each in NG+ (As confirmed by @miR, burning an ascetic will not allow you to buy them).
Hope this helps a bit.
Kill Elana(only once) in the first DLC and bonfire ascetic the first bonfire in the DLC, each ascetic nets you 5 cracked red eye orbs, 3 twinkling, 1 elizabeth mushroom. so basically you're getting almost 100k worth of items for 1 ascetic which you can buy for 7.5k and you dont need to buy any if you pick up all the ascetics throughout the game, youll have plenty to get 99 CREO and 99 twinkling titanite. If you run out of ascetics use the CREO in the chasm of old and get more 1 CREO for 1 Ascetic if you win.