There are a lot of games out there that assume that players will use WASD as their keys to move the player (ie. most flash games). I don't use WASD as my player control when using keyboard and mouse.
I tend to use a AERG (Left-Up-Down-Right) control scheme, due to mainly the size of my hand and WASD feeling too cramped. Plus playing for small periods of time (> 30 min) on WASD makes my hand hurt. The problem that I have is that a lot of the Crouch/Dodge/Target/Run keys are bound to the Left-Ctrl/Alt/Shift which I have a problem using effectively with this layout. I tend to rebind them around my left index finger (on the G). I find that it is sometimes difficult to play in this manner as I don't have a spare finger for extra key presses and sometimes multiple keys are required to be pressed at the same time.
I don't really want to use a controller, and I need something that doesn't put strain on my hands. Are there any improvements/layouts that I could use to reduce repetitive stress and still allow optimal control?