For me the first boss went down pretty easy. I had to adjust my play style, but I already had a few EMP grenades in the inventory...so I went with EMP, then unload combat rifle clip into upper torso, run/hide. Wash, rinse, repeat. Also I tossed out a few frags since I knew I could use them on the fight.
The second boss fight was more confusing for me, I ran a lot, and died from tossing EMP grenades. Then I figured we'd just play hide n seek, and the boss would have to find me by coming through my frag mine field. That worked really well.
Thats as far as I've gotten. I feel like the hacker build has gotten me a lot more EXP and Credits than my room mate who's taken a non-hacker, stealth based approach. Before the return to China segment I actually had 15 unspent praxis points I had bought/earned by hacking everything in the game that I could. At wich point I wound up buying dermal shielding, flash suppressant, lung rebreather, and anything I thought would help me out in the "Black Hawk Down" moment.