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After discovering the truth behind the anchor of Picus, Eliza Cassan, I am confronted by someone with augmentations that match or even defeat mine.

Any damage I do seems quickly repaired, and once she cloaks I can't find her any more.

What tactics should I use to beat her?

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A few blasts (2 on easy) of the typhoon aug without the upgrade will take her down without having to use any tactics or skill whatsoever. I highly recommend having it for bosses if you're playing an otherwise weak stealth/exploration character. –  Fambida Sep 4 '11 at 8:29
    
in the lockers there are emp landmines –  user47101 Apr 17 '13 at 4:31

8 Answers 8

up vote 14 down vote accepted

Note that Eliza will always warn you before the boss uncloaks to charge you in melee. Try to position yourself around one of the large power cells around the room. When the boss uncloaks to charge you, place yourself between her and the cell, and she'll charge the cell, take damage, and be temporarily disabled (I've found that the easiest way on the hardest difficulty to do this is to jump over her as she charges, but I'm not sure if this is possible without the cybernetic leg prosthesis). Feel free to squeeze off a few head-shots with your weapon of choice while she's incapacitated if you have the electricity-shield upgrade on your dermal armor;otherwise, jump like a bunny on crack if the electricity damages you to avoid taking the full amount of damage. To my knowledge, there is no immediate "safe" place to hide from the electricity damage, but I could be wrong here.

If she still has some health left after charging all four cells, a fairly easy way to get some decent damage in is to stun her with your stun gun or EMP grenades and shoot her a few times with your weapon of choice. Then run. Run like demon monkeys are after you and hide like a scared NPC.

You can also "see" her while she's cloaked if you have the smart vision augmentation; this comes in handy to either plan surprise attacks or get to a safer location, as the boss moves quite slowly while cloaked, even on the hardest difficulty.

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This is the answer I was looking for. Note that the boss fight is over after charging all four cells, always. –  user56 Aug 31 '11 at 11:46
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Really? I thought I got her into all four and she still had a bit of life left for me to shoot away...maybe I missed one and didn't notice...it was a tense few minutes ;P –  Artless Sep 1 '11 at 5:03
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@ArdaXi - I have to agree with Artless here - on my hardest difficulty playthrough, hitting the four cells wasn't enough - I still had to run around and shoot at her some more afterwards. –  Raven Dreamer Sep 26 '11 at 18:16
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You can also shoot the power cells to make them go off. If you have the EMP protection (dermal armour) and Typhoon augs you can simply shoot the power cells when she gets near, then get in close and hit her with the Typhoon. Finishes this fight fast. –  GShenanigan Sep 26 '11 at 20:37
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+1 for "jump like a bunny on crack", "run like demon monkeys" and "hide like a scared NPC" –  Coomie Sep 27 '11 at 1:09

It took me about 20 stun gun shots to kill this boss on a non-lethal playthrough.

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You know that boss fights don't count for Pacifist, right? –  user56 Aug 29 '11 at 20:43
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Yeah I know but at the time its was easier that way she never moved and i did not take damage mind you I was also on the hardest difficulty. –  ken Aug 29 '11 at 21:42
    
Thanks, great tip. I didn't realize the stun gun actually did damage, I thought it just held her still so I could ineffectively pepper her with my sissy little cap gun. I found other ways to win, but they didn't make sense for a sneaker-build: either I had to spend praxis points on things that made no sense, or pick up a heavy weapon to barely survive a brutal slug-fest. –  Feral Chimp Aug 31 '11 at 14:03
    
@AndyGiesler I beg to differ. EMP shielding is very helpful on a sneaker-build, certain out-of-the-way paths are electrocuted. –  user56 Sep 3 '11 at 22:44
    
I love the smell of stun-locking. Let me be clear, it's possible to keep the target from moving at all by continuous application of the stun gun. –  NiteCyper Apr 17 '13 at 11:39

You haven't mentioned what you have in your inventory or what augments you have chosen.

You should try and listen to her footsteps when she is cloaked. You can easily tell the direction she is approaching from. As soon as she uncloaks, move away from her and try shooting her at the same time. I also read somewhere that you can watch the wet floor for footsteps to find out where she is. Personally, I didn't find this to be of much use.

She usually stops after that initial charge and launches an attack with her augments. If you have an EMP grenade you can disable her for a few seconds and empty your arsenal at her. If you have some kind of fast firing weapon like the heavy rifle or combat rifle or machine pistol, it really helps. You can also move in closer and launch your Typhoon Augment(if you have it) after the EMP.

If you don't have any lethal weapons on you, you can look in the lockers to the sides of the circular room. You will find some weapons and ammo. This is easier if you have cloak augment.

When she is charges and fires at you at the same time just hide, and use your hypostims or painkillers. I think you can find some in the same lockers I mentioned above.

And a bit of advice for the future bosses in the game: even if you are going for the pacifist play-through for the rest of the game, keep lethal weapons in your inventory for the boss fights at least. And EMP and Gas grenades really help in slowing them down.

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The reason I didn't include my own augments/arsenal is because I want other users stumbling on this question to be helped too, regardless of their choices. (Including, possibly, a second playthrough by me) –  user56 Aug 29 '11 at 14:33
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I found that the combination of EMP/stun gun and then emptying a combat rifle (or machine pistol) magazine in their face from up close whilst they're stunned made boss fights almost too easy (and definitely very quick - I think I may have missed out on some of Eliza's comments in that fight because of it). –  Ingmar Aug 30 '11 at 17:44
    
The footsteps in the water were the only way I could tell where she was. –  recursive Aug 31 '11 at 5:15

You can stand there then as soon as she uncloaks and moves towards you. Hit the typhoon and she'll be stunned for a few seconds. Then shoot her in the head with a rapid fire gun. It only took me 2 hits with the typhoon this way to end the fight.

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I found watching the water and chasing her footsteps while she was cloaked helpful for surprise attacks.

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I managed to get to this fight but only had a Machine Gun, pistol and 1 health and 2 energy buffs. I worked out how to stun her but didn't have enough ammo and died :(

To stop her, just shoot the power cells which sets off an electrical charge that temporarily disables her, but this also electrocutes you a bit.

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There is plenty of ammo (and some weapons) in the lockers spread out around the outer wall of the room. –  Ingmar Aug 30 '11 at 17:45

I kept dying and dying from the very first power cell electrocution, so I went to a previous save file for enough Praxis and got the EMP Shielding augmentation. Then I was able to survive electrocution and shoot the boss while she was stunned.

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In the recently released Director's Cut version of the game, you can hack a door on either side of the arena. You can find a pocket secretary to give you the code in one of the lockers near one of the doors. Once you're upstairs, look for another pad to hack near the wall. You can either burst through this wall or hack the pad to disable the lasers in the middle of the room. Now hack the computer in the middle of the room and you can turn the turrets against the boss and she should die quite fast.

While doing all this, either use EMP grenades to stun her or avoid her attacks by sprinting right before she attacks you. She will give up after a few attempts.

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protected by fredley Apr 17 '13 at 12:47

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