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Mom keeps haunting my dreams, and after countless battles with this horrible woman, I only find myself badly beaten up.

Are there any strategies or items that can make this boss fight somewhat easier?

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I can't help but be concerned at the kind of traffic this will bring to the site. –  Wipqozn Oct 1 '11 at 23:26
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Any publicity is good publicity, right? –  Doozer Blake Oct 2 '11 at 3:36
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Cast a level 5 Charm on her by doing your homework before you play computer games? –  TLP Oct 2 '11 at 12:02
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@Wipqozn You say "concerned at", I say delighted by. –  Fambida Oct 26 '11 at 14:59

4 Answers 4

up vote 15 down vote accepted

I have just managed to kill Mom, after a few previous attempts that did not go so well. What made it possible for me were two things, basically:

  • High health: I had 7 full hearts when I faced mom. This was partially due to luck (lots of extra health pickups/pills) and also due to me hoarding money (which allowed me to fill up on health from the shop and arcade on the same level before the final showdown). I beat mom with at least 2 hearts to spare, though (possibly 3... I was too busy not dying to pay proper attention).
  • High damage: I was lucky enough to have some decent damage by the time I faced mom by picking up a small rock, and by clinging to a strength tarot card until that very showdown. This allowed me to empty Mom's health bar quickly, and was essential in handling the lesser baddies that Mom keeps spawning (I also picked up the common cold for some poison damage over time, which was quite handy).

Of course, this would not have helped me without at least a bit of strategy:

  • Clear out the stage. Mom's stage usually contains an assortment of rocks. Try to get rid of them as fast as you can, as all they do is limit your maneuverability (also, they might hide a handy power-up, rarely). Of course, if it's not getting hurt or clearing out some rocks, leave the rocks alone. Be aware that Mom's stomp also destroys rocks.
  • Always be mindful of the shadow indicating Mom's incoming stomp. At the very least get out of the way, but if you really want to make your life easier try to lure troublesome enemies into the damage area. I haven't seen a spawned baddy that survived a single stomp.
  • If you have to stay still, do it in one of the corners or at the center of the room. Mom can damage you directly if you stand too close to one of the four doors on her stage, and this will also let you keep an initial distance from spawning baddies (which spawn from the doors). Actually, try not to spend too much time in front of the doors regardless, even while running around.
  • If there's nothing trying to kill you, hug a wall, pick a door and shoot at it. Most chances are one of Mom's body parts will poke through one or more of the doors soon enough, and there's no reason not to cash in on that for some heavy damage.

I managed to pull this off without using my item at all (I had Mom's pad). I suspect that if I were to have a useful item (such as my little unicorn), the battle would have been even easier.

Also, there is an item called the Bible that makes the fight against Mom amazingly easy, as it instantly kills her when used (and it instantly kills the real final boss as well!).

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The Bible is actually available before you kill Mom: my first (and so far only) Mom kill used the Bible. –  murgatroid99 Oct 16 '11 at 0:41
    
Thanks @murgatroid99, I edited my answer in light of your insight. –  Aubergine Oct 16 '11 at 14:37

just beat mom on binding of Isaac wrath of lamb expansion pack, slightly harder than original but possible, I got coal off the devil like boss, then the cats paw off the devil statue, and poison ability later on, not sure what coal does but it definitely helped

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One does not simply walk into the basement and kill Mom.

Games of BoI are made easier or harder by the combinations of items that you find. Taking down Mom is more than just a matter of attack patterns and boss strategies. This is more of a whole-game strategy that will make fighting Mom easier.

  • Pick Maggie.
  • Save up 15 coins however you can get them.
  • Shop the stores and look for an item called "The Habit". It looks like a nun hat and you can buy it for 15 coins. If you've got spare coins over 15 and you encounter bums, they can also reward you with a store item, but this can be unreliable. The battery is also nice but The Habit is your main goal.

Got the Yum Heart (which you get if you start with Maggie) and The Habit? Congratulations, you've got one of the most powerful item combinations you can get without getting into harder unlockables. The Habit will fill up your item charge when you get hit, and using the Yum Heart will give you a heart back. This makes you pretty much invincible to half heart sources of damage.

Mom's stomp and Mom's hand through the doors are one heart damage sources, so during the fight itself, concentrate on dodging the foot, shooting the foot, staying away from the doors, and of course activating the Yum Heart whenever you can.

On the subject of The Habit, there's pretty much no reason not to look for this item. It's good for nearly any strategy and astounding in conjunction with certain other items.

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Well, for me the boss fight with mom took FOREVER to beat. So when I did, I wasn't surprised because of 3 handy power-ups(or upgrades). 1. The brimstone upgrade. Sure I had to wait for it to charge, but the damage it deals is AMAZING! 2. This is not so much of a power-up, but getting a lot of meals in can be handy. I got the three meals, and a dessert. These can really save you. 3. Getting in a LOT of damage upgrades, plus speed upgrades can really help. You will be able to avoid mom while dealing damage to her other body parts.
I hope you found this advice helpfull.

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