I think it depends on which Macbook Pro you have. Look at the recommended settings:
Dragon Age: Origins (Mac) Minimum System Requirements
- OS: Mac OS X 10.6.2 Snow Leopard or higher (10.5.x Leopard NOT supported)
- Processor: Intel Core 2 Duo Processor 2.0 GHz
- Memory: 2 GB RAM
- Graphics: ATI X1600 or NVIDIA 7300 or greater
- At least 17 GB of hard drive space for installation
- This game will not run on PowerPC (G3/G4/G5)-based Mac systems,
or Intel GMA class of video cards.
Dragon Age: Origins (Mac) Recommended System Requirements
- Processor: Intel Core 2 Duo Processor 2.4 GHz or higher
- Memory: 4 GB RAM or more
- Graphics: ATI 3870 or NVIDIA 8600 or greater
As for how it will run, VGBlogger has a nice Mac vs. PC review of Dragon Age: Origins. It comes down to being a good port performance-wise, but some of the features are missing. For instance, there seems to be problems with getting DLC in the Mac version:
There were concerns about the Mac version from the moment of release, because the nicely-done DLC purchase and DLC system used for the PC version simply didn’t work for the Mac version. For example, on the PC if you bought the standard version you could buy extra content such as the Warden’s Keep (normally included as part of the Deluxe Digital version) through an in-game vendor. On the Mac version if you didn’t buy the Deluxe Digital version you can never get the Warden’s Keep. Ever. Period.
I'd suggest reading over that review to see if you can live with the shortcomings. The PC version can chug on my rig (Core i7, GTX 260) in heavy battles, but on low settings that might not be a problem. One last thing: this game plays havoc with your hard drive, so if you are in the least bit concerned about your laptop's hard drive, I would consider getting it for a desktop (or for the Xbox 360, if you have one and don't mind missing out on some of the tactical gameplay).