I have over 120 Hours in Skyrim on PC. I've completed the civil war (stormcloak) and the main quest. I'm now trying to complete the Dark Brotherhood, but anytime I go anywhere near Soltidue to do "Bound Until Death", by walking from a nearby location or fast-travel, the game crashes with a "Skyrim has encountered a problem" in front of a black screen, not a normal crash to desktop that many get randomly. This affects not just Solitude but most of the areas immediately around it. I've tried console coc and cow commands to get there and they all crash the game one way or another. I can go pretty much everywhere else without a problem, but I recently had the same problem with the Wreck of the Winter War. My assumption is more and more regions will get bugged as time goes on.
Does anyone know of any workarounds?