One of my current strategies in Dungeons of Dredmor is to close myself in a room in order to heal. Sometimes also I'll escape via the Satanic Displacement Glyph system. Thus far, I've not found any enemies that can get to me when I do one of these things, so I'm assuming when I do them that I'm safe from harm.
However, I'm only on the second level of the dungeon. (This is the furthest I've ever gotten! wooo!) Will this strategy eventually fail me?