This is a pretty simple one. Are there any missions in the game that are mutually exclusive? That is, are there any two or more missions that are uncompletable in a single playthrough?
For example, say the missions Kill Guys #5, Fetch Quest #11, and Planet Scanner #19 are available to complete. When I finish mission Fetch Quest #11, mission Kill Guys #5 becomes unavailable. However, at the same time, if I finish Kill Guys #5, mission Fetch Quest #11 becomes unavailable. Therefore, it's impossible to complete Kill Guys #5 and Fetch Quest #11 in a single playthrough due to the missions canceling each other out.
Are there any actual scenarios like the example above in the game?