I beat Mom for the first time yesterday and continued into the Womb on a second playthrough. I was doing pretty well (playing Cain, had 6-7 hearts, maxed out tears, high damage, 99 coins and keys, etc.), but noticed a significant difficulty difference in the Womb.
What is the differences between the pre-Mom levels (the Basement, Caves, and Depths) and the post-Mom levels (I know I took more damage, at least)?
I didn't find any shops or item rooms in one and a half levels in the Womb - is that a coincidence, or do I need to just hope all my items from before Mom can get me through the rest of the game?