So I was playing the Tuchanka missions, but Eve died on me, and we can't have that, so I dug up some save editors and changed my ME2 plot choice so that I saved Maelon's cure. It's weird that she dies at all, since I can't imagine why I would've opted to destroy Maelon's cure in the first place since it's apparently a paragon choice to save it - could this be a glitch? I then tried to replay the last Tuchanka mission, but she still dies. All of my squadmates were loyal at the end of ME2, and all of them survived the suicide mission.
I'm an avid game-saver, so my question is: how far back in the storyline do I have to go for the Maelon's cure boolean to take effect and change the outcome, i.e. to save Eve and keep the Krogans in check?