I have a Warrior/Rogue-heavy character that has gotten down to the bottom floor once now. When I got there, Dredmor used a spell that killed me after one or two rounds.
I'm considering adding Emomancy into the mix so I can get Dampening Field of Angst (the antimagic field). Since I play on perma-death, I can't easily test this. I don't want to waste a skill slot for a single spell that might not even work.
Does this spell affect him, or does he resist it like the final boss in most games?