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This door wants to eat me! What will happen if I go in? What is this sorcery?

Door with teeth from Binding of Isaac

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The question is, can you resist the urge to try it? – Hex May 28 '12 at 19:44
The curse room will also let you into the level secret if the secret is adjacent to the curse room at the cost of an additional heart. – Steinin Feb 9 '13 at 11:35
up vote 6 down vote accepted

When you pass through that door, in either direction, you take half a heart of damage. On the other side you will usually find red chests, which usually have better stuff than normal chests (like two pills or an item), but sometimes have bad stuff like enemies or troll bombs that follow you.

See also: Curse Room (Binding of Isaac wiki)

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