I run P0~P2 production in 0.0 space to pretty much pay out most of a PLEX for my eve guys every month. In high-sec, I don't imagine the setting to make a decent amount of side cash to be any different, though, except maybe your yields.
I use a setup that relies on channeling everything through a single launchpad, using three basic factories each for two resources, and three advanced processors to take product from one of each of the basics to filter into a P2, which is sent to the launchpad. This can easily produce POS goods such as Enriched Uranium, Coolant, Transmitters, and other stuff on single planets, provided you can upgrade your command centers accordingly. Plus some of these goods are consistently in good demand
You could also check out this video. Forgive any, uh, colourful language, as it's done by an angry member of GoonSwarm
Drop it on a plasma planet. Get Enriched Uranium. Get money, get paid.
- Don't attempt PI until you get both Command Center Upgrades 4 and Interplanetary Consolidation 4. Don't run extraction cycles shorter than 24 hours. Don't do PI on planets too far away from freight service pickup points or market hubs.
- Your goal is to produce 432,000 P0s of each type per day for a setup with 3 Advanced Industry Facilities.
- If you're finding it hard to meet that number, do 2+2 Basic Industry Facilities and 2 Advanced Industry Facilities. Your goal will now be 288,000 P0s per day. Obviously this will be less money but its also less effort.
- With CCU4 you can have 6 basic industry, 3 advanced industry, and 6 extractor heads on most planets. This should allow you to comfortably run 24 hour extraction cycles while meeting the quota your factories' need. If the planet has been plundered by your fellow goons, however, you'll need CCU5 to run such a setup. CCU5 is the AWU5 of PI, and highly recommended because it makes you not want to cut yourself when you do PI on several characters.
- You don't technically need planetology skills, but they're highly recommended. They make it easier to find resource hotspots on planets.
- Why plasma planets? Because they make enriched uranium. The goal of this setup is low effort, and that means products that will always be in stable demand (read: POS fuel) and at a good price point, which considering planet/resource rarity means that enriched uranium (only on plasma) and coolant (only on storm, in practice) will be ahead of the curve. Q&A near the end touches more on this.
- Place structures as close as possible, for less powergrid drain from your links.
- If you find that your launchpad is overflowing with P0s, consider adding an Storage Facility to the setup. Route both Extractor outputs to it, and keep all Industry Facility output (P1-P2) to the Launchpad.