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I know that many of the skills available in game are down to playstyle but I've heard that training certain abilities, for example Swimming don't really provide much of a bonus and can prevent you from being powerful enough by the end of the game to perform some of the actions required (like hacking doors or lock picking) and can make the game more difficult near the end of the game.

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Are there any of the other skills that I should avoid due to them being generally useless?

Are there any skills (other than my primary weapon skill, obviously) that I should definitely take?

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just a little tip near the beginning. if you take your points out of pistol before the game starts, you'll have level 2 pistol again so you get a little more skill points –  z ' Dec 19 '12 at 18:46
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@spartacus I didn't know this, thanks! That's like an entire additional skill trained... –  kalina Dec 19 '12 at 19:34

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up vote 6 down vote accepted

The lovely thing about Deus Ex is that the answer to this (and many similar questions) is: "It depends on you."

That is, the usefulness (or lack thereof) of nearly any skill set is almost entirely dependent upon your play style and strategy. For most missions in Deus Ex, "TIMTOWTDI" is fully applicable.

So, you want to be a super-stealth sniper assassin whose enemies never see or hear him coming? Beef up on Weapons: Rifle, Weapons: Low-Tech, Lockpicking, Electronics, and Computer. Dump Weapons: Demolition, Weapons: Pistol, Weapons: Heavy, and Medicine. Even Swimming could be useful here, for finding unconventional paths to sneak around your enemies.

Wanna get up close and personal, watching the life drain out of your enemies eyes as you annihilate them? Load up Weapons: Heavy, Weapons: Pistol, Weapons: Low-Tech, Medicine, and Environmental Training. Stay away from things like Lockpicking and Weapons: Demolition.

By far, this has to be my favorite feature of the game - the fact that you are almost never railroaded and can, more often than not, choose your own way to beat the game.

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I haven't played the original Deus Ex (I know, I know), but I can't imagine Swimming being as useful as Lockpicking or Electronics. Then again, it is significantly cheaper. –  kotekzot Dec 19 '12 at 18:29
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You ought to say that for pretty much any skill you don't take, there's an aug or item that covers it. The reason why people say to not bother with swimming is because the (fairly common) Rebreather item essentially gives you unlimited lung capacity, and you never really need to swim fast. –  Tacroy Dec 19 '12 at 19:05
    
@Tacroy Good point there as well. I just haven't played in awhile. –  Iszi Dec 19 '12 at 19:10
    
This. I will add that the amount of skills you have depends on what your goals are in the game. But I will say that swimming is pretty useless past trained (I do it at the beginning so I can explore the shipwreck) since there are enough rebreathers around to handle any extended trips under water you have if you plan well. Demolition is only useful, for most part, on extending trigger times for disabling planted devices. And there's enough lockpicks and multitools around (if you look) to only really need trained skill on those. But I suppose if you want to do a speedrun... –  Glenn1234 Dec 29 '12 at 23:24

Regeneration obsoletes the Medicine and Swimming skills.

The Regeneration augmentation covers a lot of other skills, augmentations, and items.

For example, Medkits are redundant if you have Regeneration (so the Medicine skill is not useful).

When swimming, Regeneration can heal you faster than you take drowning damage, so Swimming and rebreathers are redundant. The hazmat suit is also redundant because Regeneration usually overcomes toxin and radiation damage. This makes the Environmental Training skill only useful for wearing Ballistic Armor and Thermoptic Camo.

Other skills

The utility of the Weapons: Low Tech skill isn't immediately obvious to new players. It is useful to those playing stealth characters or pacifist characters, because it makes the Riot Prod and the Baton into extremely effective weapons. Master Low-Tech Weapons with a L2 Combat Strength Aug and you can use the Dragon's Tooth Sword to break nearly anything breakable in the game, including cameras, turrets, and alarm panels.

I have never taken Weapons: Demolition - the grenades already work plenty good and disarming them is pretty easy even on untrained.

Starting skills

Note that you can un-train Weapons: Pistols at character creation. This allows you to begin play with 6,575 skill points.

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