The Binding of Isaac is a randomly generated action RPG shooter with heavy Rogue-like elements.

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What determines how much damage a blue fly does?

I've had trips into the basement where blue flies seemed to do almost cosmetic damage, and trips into the dungeon where the blue flies were a murderous death swarm. What items or statistics make blue ...
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1answer
298 views

How do I know what all this stuff does?

This game has all kinds of items, but everytime I find one there doesn't seem to be a description. How do I know what all this stuff does?
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What are each of the challenges?

On the main menu, there are a list of challenges you can attempt. Clicking one starts the game, presumably with differences depending on the challenge. What is the locked challenge, and what is ...
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1answer
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Do challenge rooms spawn specific enemy waves?

I've gone through my share of Binding of Isaac playthroughs, and almost always bother with looting challenge rooms, which in turn has me fighting three waves of enemies. Having done this enough ...
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3answers
723 views

What counts as damage for the no damage achievements?

In the Binding of Isaac, there are various things that decrease total health in some way. Which of those things count as damage for the "Complete the X without taking damage achievements" (Basement ...
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1answer
1k views

Whats the difference between rare and normal bosses?

So I recently came across, what i assume is a rare boss spawn: I noticed with this one, that his color changed from white, to orangeish. His speed increased a lot, and made it hard to dodge. And ...
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655 views

How do secret rooms work in Wrath of the Lamb?

Without the DLC, the secret room would've been here guaranteed, as it's the only non-room area with three or more rooms around it: Instead, I lose. I get nothing. Good day, sir. Why is that? What ...
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5answers
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Can I prevent unwanted items from appearing more than once in the same playthrough?

It happens every time! I go to the item room and find Teleport. I don't need Teleport, so I leave it. Then the next item I find is another Teleport! This will happen either in the challenge room ...
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3answers
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How do I Unlock the “???” Character?

I just found out (in the wiki) that there's a character called ??? in Binding of Isaac. However, the page doesn't say how to unlock him. I also haven't had immediate luck on google (try googling "???" ...
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1answer
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What will happen if I take an item costing 3 soul hearts but I don't have enough?

I'm currently the the Devil room and am being offered a Sister Maggie for 3 soul hearts. The predicament is that I only have 1 soul heart. What will happen if I try to take Sister Maggie?
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Is there anything special about the blood rooms?

Typically, only special rooms are marked on the map (item rooms, shops, arcades, bosses, deadly sins, etc.). What's special about the blood room shown below? I tried hurting myself on the spikes, and ...
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Does every floor contain a secret room?

Does every floor contain a secret room (entered via bombed wall or having X-Ray Specs), including the Womb and Sheol?
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12k views

How does Wrath of the Lamb change the Binding of Isaac?

I'm evaluating whether or not I should get this rather cheap DLC and I've boiled it down to the two following questions. I'll draw the conclusions myself. Does the DLC change the game forever? Is it ...
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447 views

Is Wrath of the Lamb available to buy anywhere besides Steam?

I see from here that the expansion is available to buy from Steam but there doesn't seem to be any alternative methods of purchase available. Does anyone know if the expansion can be bought anywhere ...
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399 views

How does the game prioritize hearts?

If I have white hearts, soul hearts, and normal hearts, in what order will they be taken when I am damaged?
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4answers
18k views

What does the Mitre do?

One of the items the Binding of Isaac expansion Wrath of the Lamb added was the Mitre. When I picked it up I just go the message "You feel blessed" I haven't noticed a change in my shots or anything. ...
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1answer
426 views

Do I need to open the chest to make it count as a win?

If instead of opening the chest I skipped it and used one of the methods to access Sheol directly (I am error room; Devil room; We need to go deeper) does it still count as a victory as far as the ...
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1answer
132 views

Do items despawn?

I just found a heart! Unfortunately, I don't need this heart, but I am 100% sure I will need it later. If I leave the heart alone long enough, will it disappear? What about coins and other items? ...
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1answer
209 views

Challenge room locked though I have full health

I thought these opened if you have full health. I actually had full + 2 blue hearts before dropping a bomb on myself before taking the screenshot. But even here I have full health... right?
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1answer
7k views

How can I change my controls?

My W key is broken but I can't find a way to edit the controls to something different.
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1answer
1k views

Can I go back to the rest of the level once I beat Mom?

Am I really leaving behind everything on the Depths 2 after I enter the boss room? I had left behind a blood donation machine and a full health pill and everything else!
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1answer
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What are the tradeoffs in using We Need to Go Deeper?

Once you have the item We Need to Go Deeper in The Binding of Isaac, why wouldn't you simply use it every time it has charged to go to the next level and bypass a large number of rooms? The only ...
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1answer
1k views

What happens if I get an Eternal Heart when I already have 12 Heart Containers?

We already know that Soul Hearts can stack indefinitely, even with 12 Heart containers. What happens with Eternal Hearts in the same situation? Are they still getting added between Heart containers ...
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1answer
951 views

My “damage” stat bar is flashing. What does it mean?

When I open the menu to look at my stats, the bar that shows damage is "flashing" (well, it looks more like it keeps increasing from "0" to "max" over and over again at high speed, hence "flashing"). ...
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1answer
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What does Fate do?

I just found a sad/dead blue head (called "Fate" when I picked it up), and now I have half of a white heart (not a soul heart) and wings. What does Fate do?
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1answer
1k views

Can “Blood Lust” take me above max damage?

Samson's starting item, Blood Lust, increases the the damage of Isaac's tears with each kill. Can it go beyond scale, as some damage multipliers do (i.e. Whore of Babylon)? What I'd like to know is ...
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2answers
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How to unlock Eve's Dead Bird?

The achievement description says: Make 2 deals with the devil in one play through. My only question is, does it count if I make two deals with the same appearance of the devil? When you meet the ...
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1answer
199 views

What does health actually mean?

The health rating on the character select screen, what is the actual meaning for it? The wiki mentions how one health is equal to one red heart container, but this is not the case. Case in point ...
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259 views

What's causing my random magnet effect?

Sometimes, I get random magnetic effects like you typically see with Magneto. What could be causing me to have these magnetic properties?
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1answer
1k views

Why does this door have teeth?

This door wants to eat me! What will happen if I go in? What is this sorcery?
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1answer
72 views

Is There Any Reason to Start with the Original Binding of Isaac?

I really want to play The Binding of Isaac but I'm not sure which version to get, so what I'm asking is this: Should I just get Rebirth? Is there any reason for me to want to play the original one ...
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1answer
175 views

What is the chance of Skatole to appear at the Shell Game?

In the Arcade room when you play the Shell Game with the beggar there is a chance of him revealing Skatole under one of the Host Skulls when betting. I know when it appears you have a 33% chance of ...
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1answer
566 views

Does buying the Treasure Map cancel the Curse of Darkness Curse?

I'm doing my first challenge run in The Binding of Isaac and I've decided to do the the first challenge on the list: Dark was the Night. This is the challenge where you automatically have the Curse of ...
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1answer
1k views

How does the new type of secret room work?

In Wrath of the Lamb, I've come across a new type of secret room that works in ways I am not familiar with (primarily, unlike the standard secret room, it doesn't appear next to multiple adjacent ...
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1answer
104 views

Can I find an arcade more than once during a playthrough?

In Binding of Isaac, can I find an arcade more than one time during my playthrough? For example, if I find an arcade during one of the Cave levels, can I find another one later in Depths?
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Is unlocking all the items enough for the Golden God achievement?

Is Golden God unlocked by unlocking every non-DLC item, or do you need to also find and pick them up?
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1answer
2k views

If I use the Ankh and manage to kill the final boss, who gets credit for the kill?

The Ankh item works this way: when you are killed it instantly teleports you to the previous room visited, turning you into ???. If, while in this state, you manage to kill Satan/Isaac, who gets the ...
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2answers
2k views

How many “curses” have been introduced in Wrath of the Lamb and what is their effect?

I've notice that any level can start with a random curse(don't know if it's the same pre-"Everything is terrible!"). Until now I've found: Curse of darkness (you cannot see the map) Curse of the ...
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2answers
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What is the stat 'Luck'?

I just used a pill and received the message "Luck Down." I'm aware of Faith, which increases your chances of finding the Bible, and I suspect this is similar. What is Luck?
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1answer
518 views

How do I unlock the “Meat 4 Evar” challenge in “The Binding of Isaac”?

I've had Wrath of the Lamb for a week, and everywhere I search, I can't find the answer. Please help!
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1answer
10k views

How do I unlock the Cathedral in the Wrath of the Lamb DLC?

I bought the Wrath of the Lamb DLC, but the Cathedral isn't unlocked yet. How is this unlocked? Is it because I haven't beaten the Sheol with all the characters yet?
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2answers
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What do you have to do to fight Isaac?

The new final boss in Wrath of the Lamb is Isaac himself, with three forms similar to The Devil. As Isaac, I got to Utero, got through it, and beat It Lives, then go to Sheol and beat The Devil - I ...
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1answer
2k views

What does the “fortune-telling” slot-machine do?

There's this new slot: What does it do? I've spent some cents only to receive cryptic phrases. The best use I've found for them is blowing them up.
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2answers
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What counts as passing on a treasure room?

On the character page, it says I have to "pass on 2 treasure rooms" in order to unlock Samson. If I enter the treasure room, but do not pick up the item, does that count as passing on it?
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2answers
1k views

Is there a blue rock equivalent in the Womb?

In Binding of Isaac, the earlier levels have blue rocks that when bombed yield usable items and/or chests. In the womb, the rocks are red and I haven't seen any that stand out from the rest. Is there ...
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2answers
130 views

Killing mom's heart with Judas not counting as an ending?

I killed mom's heart with Isaac and got Judas and ending 1. Then I killed her with Judas and completed the game with credits, but I don't see an additional ending. Is it still counting as one of the ...
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1answer
32k views

Which Trinkets are available in Wrath of the Lamb?

I just found a new item called Tick in Wrath of the Lamp DLC and discovered that is a 'Trinket'. In the meanwhile while playing I found other trinkets like Aces of Spades, Push Pin, 2 of Diamonds and ...
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3answers
800 views

Can I get to Sheol through a challenge run?

So, I need to beat Sheol with Isaac in The Binding of Isaac, can I select the "Doctors Revenge" challenge (which requires you to beat Mom's Heart) and maybe get lucky with a demon room on the Mom's ...
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1answer
859 views

What counts as beating a challenge in Binding of Isaac?

I've been trying to work through the challenges introduced in Wrath of the Lamb to unlock stuff in the Binding of Issac,but have noticed that I'm not winning the challenges after beating 'It Lives'. ...
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1answer
482 views

Are Sheol achievements locked now with Wrath of the Lamb?

I had most achievements before the Wrath of the Lamb update. Most of them, that is, except for the ones given for completing Sheol with Judas and Eve. I then completed the full game with Judas and got ...