The Binding of Isaac is a randomly generated action RPG shooter with heavy Rogue-like elements.

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6
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5answers
3k views

Can I prevent unwanted items from appearing more than once in the same playthrough?

It happens every time! I go to the item room and find Teleport. I don't need Teleport, so I leave it. Then the next item I find is another Teleport! This will happen either in the challenge room ...
3
votes
2answers
1k views

Are the no-damage achievements necessary to get “Golden God” and “Platinum God”?

In the base game there are five achievements that require you to complete a "layer" of the basement without taking damage. Are these necessary to get the "Golden God" and the "Platinum God" ...
1
vote
1answer
41 views

What do you need for Platinum God?

I have 95/97 secrets and a full collection of 198 items. Click to embiggen: All the achievements and secrets I'm now missing are AFAIK (and astats.nl confirms): Spelunker Boy Mama's Boy Platinum ...
0
votes
2answers
108 views

Do Soul Hearts count as tribute hearts?

So I have been playing The Binding of Isaac, and you can have red hearts, and blue hearts (Known as Soul Hearts) and I was wondering, does using the Curse Room Door or doing deals with the devil ...
0
votes
2answers
71 views

Which tarot card gives the bigger damage boost: The Empress, The Devil or Strength?

The Empress - Puts you into curse state for a room The Devil - Acts as a one-time Book of Belial charge Strength - Gives you a temporary +1 HP and boosts your damage. All three of these tarot cards ...
9
votes
2answers
2k views

What are all of the rules that determine where secret rooms appear?

The Binding of Isaac with the Wrath of the Lamb expansion has two different secret rooms on each floor. It seems that there are some specific rules that determine where the rooms can appear on the ...
6
votes
3answers
12k views

How do I Unlock the “???” Character?

I just found out (in the wiki) that there's a character called ??? in Binding of Isaac. However, the page doesn't say how to unlock him. I also haven't had immediate luck on google (try googling "???" ...
6
votes
4answers
1k views

Does every floor contain a secret room?

Does every floor contain a secret room (entered via bombed wall or having X-Ray Specs), including the Womb and Sheol?
40
votes
2answers
4k views

How can I increase my chances of getting cancer?

In a recent Binding of Isaac playthrough I encountered an item which I had not seen before. It was called "Cancer", and it seemed to increase my DPS considerably. However, since then I have only ...
6
votes
4answers
12k views

Is there anything special about the blood rooms?

Typically, only special rooms are marked on the map (item rooms, shops, arcades, bosses, deadly sins, etc.). What's special about the blood room shown below? I tried hurting myself on the spikes, and ...
19
votes
2answers
32k views

Is it possible to save in Binding of Isaac?

I know this is kind of silly but is it possible to save current progress? So far I've been leaving the game running so when I return I can attempt to finish the level but it would be nice to just ...
38
votes
4answers
7k views

How can I kill Mom?

Mom keeps haunting my dreams, and after countless battles with this horrible woman, I only find myself badly beaten up. Are there any strategies or items that can make this boss fight somewhat ...
-1
votes
1answer
423 views

What does the Spider Mod add?

I am thinking about downloading the spider mod for TBOI for the cool tweaks I heard it has, but I can't find information about them. What exactly does the spider mod add?
3
votes
1answer
50 views

Does collecting Dr. Fetus increase odds of finding other bomb-related pick-ups?

In two recent playthroughs, I've picked up Dr. Fetus early on, followed shortly by other bomb-type pickups - Bobby Bomb, Mr. Mega. I seldom see these pickups, so I'm wondering if gaining Dr. Fetus ...
4
votes
2answers
83 views

Killing mom's heart with Judas not counting as an ending?

I killed mom's heart with Isaac and got Judas and ending 1. Then I killed her with Judas and completed the game with credits, but I don't see an additional ending. Is it still counting as one of the ...
11
votes
2answers
13k views

What are the white hearts?

Apparently multiple items can give you white hearts, like the ones given by Fate. What are these white hearts? What do they do, and what can give them to you?
7
votes
2answers
598 views

How do secret rooms work in Wrath of the Lamb?

Without the DLC, the secret room would've been here guaranteed, as it's the only non-room area with three or more rooms around it: Instead, I lose. I get nothing. Good day, sir. Why is that? What ...
0
votes
3answers
312 views

Why my cellar changed and now is full of spider webs?

My basement cellar texture changed and now rooms are full of spider webs and fast annoying spiders. What's happened? Any hints how to go back and how to kill these spiderlings?
17
votes
5answers
71k views

How to setup the joypad for Binding of Isaac?

It seems that Binding of Isaac supports joypad, but simply connecting XBox 360 joypad does not work. Do you know how to setup it?
18
votes
3answers
14k views

How do you open the barred doors in the Binding of Isaac?

These doors are grey and usually (always?) open into a "weapon" room, i.e. there is a weapon on the minimap for them. I've gotten in two, but it was very non-obvious what I did to open the doors. For ...
6
votes
1answer
1k views

What will happen if I take an item costing 3 soul hearts but I don't have enough?

I'm currently the the Devil room and am being offered a Sister Maggie for 3 soul hearts. The predicament is that I only have 1 soul heart. What will happen if I try to take Sister Maggie?
2
votes
1answer
165 views

How do I “make a deal with the devil”?

How exactly do I make a deal with the devil? I'm trying to unlock Eve (the one with the dead bird).
25
votes
3answers
19k views

The Binding of Isaac just got harder, but how?

I have just finished my sixth and seventh full runs of The Binding of Isaac. After completing the sixth run, you do not unlock a new item but instead you just get the "Everything's Terrible!" ...
5
votes
1answer
114 views

Challenge room locked though I have full health

I thought these opened if you have full health. I actually had full + 2 blue hearts before dropping a bomb on myself before taking the screenshot. But even here I have full health... right?
2
votes
1answer
2k views

When do I fight Satan?

I killed mom (heart) 4 times but still there's no Satan at final. When do I fight Satan? What should I do? Thank you.
6
votes
2answers
329 views

What determines how much damage a blue fly does?

I've had trips into the basement where blue flies seemed to do almost cosmetic damage, and trips into the dungeon where the blue flies were a murderous death swarm. What items or statistics make blue ...
8
votes
1answer
3k views

What happens if I complete the title screen puzzle?

I have beaten Isaac the Cathedral level once, and when I returned to the title screen, there was a rectangle with what appeared to be a piece of a puzzle in it. I infer that I can complete the puzzle ...
0
votes
2answers
1k views

Dependency is not satisfiable: libgdk-pixbuf2.0-0 error when installing Binding of Isaac

I'm trying to install Binding of Isaac on my Debian machine, when I try to install the .deb installation package with GDebi, I get the error Error: Dependency is not satisfiable: ...
10
votes
3answers
895 views

Are there always enough keys on a level?

On a certain level of this basement, I found 2 locked doors but only 1 key. I think I have cleared out everything I can from this level but I still only found one key. Are there always as many keys ...
11
votes
2answers
6k views

Is it wise to try unrecognized pills that I find?

While playing the game "The Binding of Isaac", one occasionly finds pills. I know that the different effects those pills can posses are mentioned here, and that in each game-run there are only 6 ...
20
votes
7answers
43k views

How to improve Binding of Isaac performance?

I cannot go past level 3/4 because when I enter in rooms full of monsters the game start lagging a lot and controls do not respond at all or with a huge delay. My configuration is not actually bad: ...
4
votes
1answer
151 views

What is the chance of Skatole to appear at the Shell Game?

In the Arcade room when you play the Shell Game with the beggar there is a chance of him revealing Skatole under one of the Host Skulls when betting. I know when it appears you have a 33% chance of ...
5
votes
1answer
5k views

How can I change my controls?

My W key is broken but I can't find a way to edit the controls to something different.
11
votes
1answer
22k views

How do I access the Binding of Isaac soundtrack?

I recently bought the Binding of Isaac + soundtrack. ...so how do I actually access the soundtrack? The soundtrack shows up when I view downloadable content via steam, and it shows that I own it in ...
4
votes
1answer
10k views

How do I unlock the Cathedral in the Wrath of the Lamb DLC?

I bought the Wrath of the Lamb DLC, but the Cathedral isn't unlocked yet. How is this unlocked? Is it because I haven't beaten the Sheol with all the characters yet?
15
votes
4answers
35k views

What am I to do when something appears on one of the levels?

After playing some more the Binding of Isaac I've come across strange messages that are triggered by certain events. For instance, when I defeated one of the bosses, I suddenly got a pop-up message ...
8
votes
3answers
4k views

How can I find the secret rooms most efficiently?

With the Wrath of the Lamb expansion, The Binding of Isaac now has two different kinds of secret rooms, and together they seem to have somewhat complex placement rules. If I can only search for these ...
9
votes
1answer
36k views

What are the controls of The Binding of Isaac?

What are all the keys used in The Binding of Isaac? I'm going to configure my joystick using one of the tools suggested at How to setup the joypad for Binding of Isaac? (Xpadder, JoyToKey, QJoyPad, ...
4
votes
2answers
4k views

What is the stat 'Luck'?

I just used a pill and received the message "Luck Down." I'm aware of Faith, which increases your chances of finding the Bible, and I suspect this is similar. What is Luck?
7
votes
3answers
555 views

What counts as damage for the no damage achievements?

In the Binding of Isaac, there are various things that decrease total health in some way. Which of those things count as damage for the "Complete the X without taking damage achievements" (Basement ...
0
votes
1answer
5k views

What does Spirit of the Night do?

I just paid two hears for Spirit of the Night (whose lower-right hand message was "Scary"). Did I just pay two hearts so that I could fly? What does "Scary" mean, and what does Spirit of the Night ...
6
votes
4answers
18k views

What does the Mitre do?

One of the items the Binding of Isaac expansion Wrath of the Lamb added was the Mitre. When I picked it up I just go the message "You feel blessed" I haven't noticed a change in my shots or anything. ...
3
votes
2answers
591 views

Can I get to Sheol through a challenge run?

So, I need to beat Sheol with Isaac in The Binding of Isaac, can I select the "Doctors Revenge" challenge (which requires you to beat Mom's Heart) and maybe get lucky with a demon room on the Mom's ...
1
vote
0answers
80 views

BoI erases my data

I got Binding of Isaac for Linux through the Humble Bundle. It works fine, and sometimes saves my data (things found, challenges unlocked, etc.), but then sometimes erases them - seemingly at ...
0
votes
0answers
63 views

Does the Lucky Foot affect the Slot machine or not? [duplicate]

So yeah the wiki says that it does increase the chances of winning at the Slot Machine but it also says that it doesn't. I would like a definitive answer to if the Lucky Foot does or does not affect ...
1
vote
1answer
938 views

My game tends to crash

I play the Binding of Isaac a lot. I'm trying to unlock the D6, so I must beat the womb as ???. But when I get to the loading screen for the womb part 1, the game always crashes. Is there a way to fix ...
9
votes
1answer
2k views

How do black hearts function?

I just started playing the Binding of Isaac and one of the pick-ups I came across was a black/blue-ish heart (much like the red ones that fill up your HP). Initially, I thought it was a sort of "heart ...
9
votes
5answers
271 views

Is there a method to beating Hosts?

Hosts are the skulls that occasionally raise themselves up to shoot at you. When they raise themselves, that is the only time you can damage them. I can't seem to find any sort of pattern and end up ...
7
votes
1answer
246 views

How do I know what all this stuff does?

This game has all kinds of items, but everytime I find one there doesn't seem to be a description. How do I know what all this stuff does?
3
votes
2answers
2k views

I found an item and it went to a weird spot on my screen. Now what?

I found an item called Match Stick. After I picked it up, it went to a weird spot on my screen: What makes this item so special that it gets to go to that part of my screen? How do I use it? Are ...