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35

The game's save data is contained in two files, both of which need to be moved between computers in order to get everything migrated properly. These files are so.sol and serial.txt. I have a Mac and a Windows machine, so I'll go ahead and list the location of said files on both platforms (if anyone has any Linux info, feel free to chip in). On the PC: ...


27

It's a warning to remind you that your health is critical, i.e. that you only have half a Heart left. As long as you're at half a regular Heart (regardless of how many Soul/Faith Hearts you have), you will soil yourself in terror each time you enter a room. (If you're playing as ???, this will happen when your Faith is critical instead, because he has no ...


23

There is no foolproof way to find the secret room (except with some of the items you can pick up, like x-ray glasses), but 99 times out of 100 you can find it with one method and a little luck. Most secret rooms are contained in between at least 3 other rooms. All you have to do is look on your minimap for 5 rooms that are all joined in a square "U" shape ...


21

According to comments on the wiki, "Everything is Terrible" makes alternate colored monsters and bosses more common. This is actually good, because alternate colored monsters tend to leave drops on kill. According to the mechanics guide, it also makes Curses more common in Wrath of the Lamb. Additionally, however, bosses drop one less heart pickup (heart, ...


21

No, it's not possible. The point of the game is to keep short playing sessions where death is a permanent threat. Not having the player be able to save the game both gets across this gameplay idea, and as a nice side effect it keeps players from abusing savegame files or saving mechanics (for example, save and ctrl+alt+del task manager quit the game, and ...


20

You can get the following pickups to cross gaps: Ladder - Cross 1 gap spaces Lord of the Pit - Gives you the permanent ability to fly Hanged Man Tarot Card - Gives you the ability to fly for your current room only, one time use Transcendence - Like Hanged Man, only a permanent upgrade The Bible - Gives you flight when used for your current room only A ...


18

The doors are tied to your health. The door will only be open if you have full health. However, the temporary HP boosts (blue hearts) can serve as a equivalent of the missing red hearts. For example: If you're missing one red heart but have one blue heart the door will open. But if you're missing two red hearts and only have one blue heart the door will ...


17

What Snailer said is partially true. Some of the popups are tied to achievement. However, all the popups that say "... has appeared in the basement" is new content being unlocked. Mostly these are new items, and mini-bosses that you can find in the latter play throughs. Like the message you got, would mean that the item "Small rock" has been unlocked, and ...


16

The Binding of Isaac wiki's got a pretty comprehensive (if slightly generalized, and minorly inaccurate) list. Remember that all cards are a single use item, so once they are used they vanish. O The Fool: Teleports the player to the starting room for that floor. I The Magician: Gives you the use of Spoon Bender (homing shots) until you leave the current ...


16

Honestly, it's all down to luck. The factors that define what you get and where are completely random. First off, when you start, the computer "rolls a dice", and depending on what you get between 1 and 7 defines your luck (item find, possibility of getting curses etc.). 1 being "Curse of the dark" every time, 7 being amazing items in every gold room, ...


15

I have just managed to kill Mom, after a few previous attempts that did not go so well. What made it possible for me were two things, basically: High health: I had 7 full hearts when I faced mom. This was partially due to luck (lots of extra health pickups/pills) and also due to me hoarding money (which allowed me to fill up on health from the shop and ...


15

The following activated items can destroy rocks: Anarchist Cookbook - Spawns 6 bombs in random locations so there's not a 100% chance that it'll break the rock you need. Bobs Rotten Head - Lets you throw a bomb in any of the 4 cardinal directions. Dead Sea Scrolls - Activates as any other random activated item, so it's super unreliable. The Doctors Remote ...


14

Here's a few videos I recorded while testing it out, and slowing the video down by 85%. ...


14

As Yves's comment points out, the only item that is even somewhat similar to what you describe is the Whore of Babylon. The item itself looks like this: You can get it either by picking it up during your playthrough or by choosing to play as Eve. If you have this item and you have exactly half a heart left, it gives the message "What a horrible night to ...


13

Unfortunately, no. In my experience, there won't always be enough keys for every door. There will be a few times when you get 2 keys, but there will be 3 locked doors, requiring you to try and decide which (if any) door you want to open. The exception to this rule is the Skeleton Key which can be found randomly in the treasure rooms or challenge rooms ...


12

According to the wiki, the only item that seems to be able to raise your stats above the maximum is The Sad Onion, which doubles the firing rate no matter its current value. I have very little personal experience with that item, so I can't confirm or deny this. The stat that I find easiest to max out is damage, as I've often managed to get quite a few ...


12

TL;DR: Yes, try every pill you find In the game, according to the list near the bottom of the items page on the wiki, there are 8 pills with definitely good effects: Bad Gas: poisons surrounding enemies Balls of Steel: gives 2 soul hearts Full Health Health Up Pretty Fly: adds a close orbiting fly Range Up Speed Up Tears Up 4 pills with definitely bad ...


11

The music files are located in whatever drive you installed Steam on, then this path: \Steam\steamapps\common\the binding of isaac\The Binding of Isaac Soundtrack Your files should be there and ready to play! There's no way to access the soundtrack through the client itself, unfortunately. If you're on a Mac you'll find that path in ...


11

Strictly speaking, whenever you lose all of your regular health you will die. However, this is not always easy to do when you have soul hearts. I'll treat each of the cases you listed individually: Blood donation machine: On levels before the womb, blood donation machines do half a heart of damage. You'll start by losing regular hearts, until you have half ...


11

The amount of times you'll need to use the machine varies a lot. I've received the bag on the first attempt multiple times, but I've also once had to use the machine 32 times before the bag finally appeared. Most of the time it's worth it to at least give it a go, as you'll generally find it around 8 attempts, which will fully heal the hearts you spent. ...


10

In Windows, the FlashAchievements.exe that ships with the game is broken for many people. I've contacted Edmund with information about a fix, not sure when that's going out but he says he's working on it after this update goes out, in the meantime the fix on this page works: http://forums.steampowered.com/forums/showthread.php?t=2216833 You want the 1.5 ...


10

It's physically impossible for you to take an item costing more soul hearts than you currently have. If you attempt to, you will just move through the item as if it doesn't exist.


10

I've been experimenting for a while with these "Champions". These are results of my observations: different colors have the same stats. I've found 3 Champion Frowning Gapers on the same level, each one of a different color. They did double damage(1 heart instead of half) and had approximately double health. They dropped a penny, a soul heart and a bomb. ...


10

All you have to do is hit the space bar.


9

To say that the Binding of Isaac supports the use of a gamepad would be a slight exaggeration. The latest patch for the game added control options to the game, which looks like this: And as you can see, the game specifically tells you to use one of the many gamepad to keyboard solutions out there, specifically JoyToKey. This thread describes the ...


9

Unlocked characters, stats, and suchlike are saved automatically, but you can't save your progress in a specific session. The game is rather short, and randomly generated each time, so this shouldn't really be a problem. You play until you die, win, or quit. Then you start over.


9

From The Binding of Isaac Wikia: Increases HP by 1 and gives 2 soul hearts. Trivia: This is a reference to "Bandage Girl" from Super Meat Boy, another game Edmund McMillian worked on. Rarely Found in Boss Rooms. Unlocked by killing four Horsemen in one playthrough, not just by collecting four Meat Cubes. This can be pretty tricky given the ...


9

Ok, let's try to answer this with the use of images. But first, a little explanation. It is known from experimental evidence (and reported also on the wiki) that the Secret Rooms (the old ones, SR from now on) and the Top Secret rooms (TSR) have the following behavior: SRs are usually surrounded by 3 or 4 other rooms, while TSRs are usually found with a ...


8

I saw this from another forum. The lag is akin to "walk on ice", so you will still move to a direction a few milliseconds after having released the directional button. There is one setting in the graphic options that will solve that. Set the details to "Low". That is it, no more lag. It is probably related to flash overall poor performances. It changes the ...


8

They are called soul hearts, and simply serve as a temporary HP boost, once you lose a blue/black heart, it's gone forever. Note that when you take damage, it will always subtract the damage from the blue/black heart(s) first.



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