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Both Whore of Babylon and Devil Room transactions only care about red hearts. The only exception is that Devil Room transactions adapt to use soul hearts when playing as ???. Whore of Babylon I'm not sure what the "Whore Of Babylon Door" is. If you meant the Whore of Babylon, it only activates based on remaining red hearts: If you have a half-heart ...


Whore of Babylon only counts "real" hearts. If you have 1 red heart or less, you get the effect, no matter how many soul hearts you have. Deals with the devil can only take away red hearts (remember this is a permanent loss), unless you are playing as ???. You can lose all your hearts this way- you will survive as long as you have soul hearts. Attempting to ...

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