I was playing Bit Dungeon for the third time in a row because i was getting frustrated with my previous scores, and noticed that on the first time I had gotten a weapon that was level 6 and had life-steal. It came from a green chest dropped from a zombie boss, and on the third time I faced the same enemy and got a level 3 spear that sucked.
So, I'm wondering if all the different rooms were completely randomized or if they could be predicted to some amount of certainty.