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After conducting some research, I do believe the answer is no. Once you have your damage maxed, Blood Lust will not increase your damage further.

On my latest play through with Samson, I picked up the Small Rock, Growth Hormones, Blood of the Martyr and a Lump of Coal, so my damage was nice and maxed. I then proceeded to face Gish, who spawns Clots quite frequently. Taking care to hit Gish just once and then proceed to kill a heap of clots before trying that again, it seemed like each of my hits still took down ~9px of Gish's health bar, which was exactly tha mount of damage I did straight through the door.

After conducting some research, I do believe the answer is no. Once you have your damage maxed, Blood Lust will not increase your damage further.

On my latest play through with Samson, I picked up the Small Rock, Growth Hormones, Blood of the Martyr and a Lump of Coal, so my damage was nice and maxed. I then proceeded to face Gish, who spawns Clots quite frequently. Taking care to hit Gish just once and then proceed to kill a heap of clots before trying that again, it seemed like each of my hits still took down ~9px of Gish's health bar, which was exactly the mount of damage I did straight through the door.

After conducting some research, I do believe the answer is yes.

On my latest play through with Samson, I picked up the Small Rock, Growth Hormones, Blood of the Martyr and a Lump of Coal, so my damage was nice and maxed. I then proceeded to face Gish, who spawns Clots quite frequently. Taking care to hit Gish just once and then proceed to kill a heap of clots before trying that again, it seemed like each of my hits still took down ~9px of Gish's health bar, which was exactly tha mount of damage I did straight through the door.

After conducting some research, I do believe the answer is no. Once you have your damage maxed, Blood Lust will not increase your damage further.

On my latest play through with Samson, I picked up the Small Rock, Growth Hormones, Blood of the Martyr and a Lump of Coal, so my damage was nice and maxed. I then proceeded to face Gish, who spawns Clots quite frequently. Taking care to hit Gish just once and then proceed to kill a heap of clots before trying that again, it seemed like each of my hits still took down ~9px of Gish's health bar, which was exactly tha mount of damage I did straight through the door.

While I can't provide any hard evidence, I do believe the answer is yes.

Seeing how damage is linked to the size of the tears you shoot (and the color too, but the size is much easier to notice), all you have to do to corroborate this is to fight a boss akin to the duke of flies.

Since the duke of flies spawns an infinite amount of flies, it soon becomes evident that your tears stop increasing in size no matter how many additional flies you kill. Also, notice that each time Blood Lust increases your damage you become slightly more red, and this also stops after several kills.

After conducting some research, I do believe the answer is yes.

On my latest play through with Samson, I picked up the Small Rock, Growth Hormones, Blood of the Martyr and a Lump of Coal, so my damage was nice and maxed. I then proceeded to face Gish, who spawns Clots quite frequently. Taking care to hit Gish just once and then proceed to kill a heap of clots before trying that again, it seemed like each of my hits still took down ~9px of Gish's health bar, which was exactly tha mount of damage I did straight through the door.