I am new to this game, and will try to optimize my game-play as much as possible. I will do this by making macros for my spells and abilities.
Are there global cooldown on spells and abilities in League of Legends?
Since this is important regarding macros to trigger spell and ability combos.
A Global Cooldown(GCD) is a cooldown which affect most if not all abilities, spells or items when using an ability, spell or item.
In most games it is there to prevent macroing/spamming of multiple instant abilities, spells or items, and usually has a set short duration independent of the ability, spell or items normal Cooldown.