Occasionally, when I press the quick save button, my game closes out, and it doesn't relaunch. I have to restart my computer for the game to launch again, however when I do, it loads the quick save. It may be possible that I'm hitting another key, or have my mouse on my other screen. Does anybody know how or why this might happen, and if I can do anything to prevent it.
There are two ways in which you can stop this:
Go into settings and disable all kinds of autosaving. That means Autosave on travel, Autosave on rest and autosave in the menu. Leave your current location so that you can fast travel anywhere, select one of the major cities like whiterun, solitude etc Cross your fingers and try to quicksave. This answer was found here
The next way in which this can be fixed is: Delete your quicksave file and then quicksave again. Make a backup first just in case. Apparently the save files have issues if they're overwritten too many times. This answer was found here
I had a similar problem but with auto saves, I just tuned off autosaving when fast-travelling, entering new areas... etc. Or the quicksave problem happened to me a little, save normally (in the quest journal menu thing) before quick saving, when you first pen your game and that should help. Or just stop using quicksave all together.