When destroying buildings -
- You get more energy which could be used for healing/bombs;
- If it was a defensive building it stops hurting you.
Other than that, is there a reason (mainly loot) that one would want to destroy all the buildings in the map?
Is the answer the same for PVE and PVP?
Most of the PVE "puzzles" seem stupidly simple if there isn't a reason to destroy the buildings, you can ignore 90% of the layout.