So I've been reading through some guides in preparation for a Clean Hands playthrough - killing absolutely no one, using the Non-Lethal option for all the assassination targets.
However there's one point that seems a bit muddled. The guides say that if going for the Clean Hands achievement, it might be a good idea to avoid Granny Rags altogether, as interacting with her leads to that bit in the Flooded district and it's very hard to get out of that without killing someone.
However, they warn, avoiding her altogether makes it impossible to get the Gentleman Callers and Street Conspiracy achievements.
Gentleman Callers is obvious, but Street Conspiracy includes the non-lethal option for the Pendletons.
So basically what I'm asking is, can you still use Slackjaw to take out the Pendletons without killing them if you avoid Granny Rags?