In Bloons TD 5, almost every tower has these following buttons:
I know what they do, but I want to know what towers I can use them on to have maximum popping.
Which to choose strongly depends on which tower you're using.
There are many ways to combine the effect of multiple towers with these to maximize effects. Of course these only come into play once you're some levels into the game. Earlier on all towers can be left on first with little effect.