There are some quests spoiler ahead so beware! I will try to keep the detail to a minimum.
Basically I am trying to clear out a certain location that has a certain deathclaw in the witch muesum.
What kind of weapon can deal substantive damage to a 30 level or higher deathclaw?
I do have a companion with me and I can sneak him/her close and deal some proxy damage that way. But we all know they take forever!
But otherwise I don't have lot of option because of the location which is indoor especially grenades and other that does aoe explosive.