Some items, such as Zhonya's Hourglass, have an Active ability rather than a Passive one, requiring you to click on the item to use the ability. Some of them require rather split second timing, the hourglass in particular, whose ability is Places your champion into Stasis for 2 seconds, rendering you invulnerable and untargetable but unable to take any actions. 90 second cooldown.

I know you can use Alt, Shift, and Ctrl for various hotkey shortcuts, but I was wondering if there was any shortcut for item usage (maybe Alt+1-6 or something?) that I'm missing.


Each item slot, 1-6, is initially bound to the corresponding number key.

You can rebind this during gameplay if you wish, but I like to simply move activated items into the 2nd slot and hit 2.

  • I had no idea you could rearrange the item order. Thanks! – FAE Sep 30 '11 at 16:07
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    @FallenAngelEyes Do note you can't rearrange items from the shop view, only from the inventory on the bottom left. – Raven Dreamer Sep 30 '11 at 16:11
  • When rebinding, you can setup extra mouse buttons not normally used. I have a "back" button on my mouse by my thumb, and set it to cast whatever's in inventory 6. Works like a charm. – Ryre Oct 4 '11 at 19:34
  • I just open my mouse program, bind my middle and thumb buttons to the numbers I use for activating items. I use 4,5 and 6, Less ordering in game as my active items are usually there after I've built them. – user36117 Oct 27 '12 at 13:09

It has always been possible to cast item y using the number of item slot. Furthermore the patch note V1.0.0.125 added :

You can now Smart Cast items (you have to manually bind the hotkeys).

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