Please keep the answer spoiler free if possible, I am curious how big the list of things to do before beating the final boss is if anything gets locked out after the final boss, or if the game reverts to a pre post game stage after beating the game.
No. After defeating calamity ganon, your save gets marked with a star, but will otherwise be reverted to where it was before you defeated calamity ganon.
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It might save weapon durability used in the fight, I don't know for sure – Unionhawk♦ Feb 17 '18 at 21:06
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1You also gain access to certain features after defeating ganon, so going for that star can be worth it – Malco Feb 20 '18 at 16:12
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2fyi it doens't save weapon durability used in the fight. I've broken weapons in that fight but got them back after the ending. – l I Mar 21 '18 at 23:34