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I'm on my first playthrough on standard difficulty, almost finished and I want to know if my unlocked prizes can be used if I start a new game on hardcore.

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Resident Evil 2 doesn’t have a typical New Game Plus mode that allows you to carry over weapons, weapon upgrades, and items into a new playthrough. There is, however, a 2nd Run mode that is unlocked after completing the game with either character which mixes up item placements, puzzle solutions, and more, should you be looking for a slightly remixed experience. This doesn’t allow you to carry over weapons and upgrades, though.

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  • Unfortunately, the text is not clear about higher difficulty Commented Jan 29, 2019 at 20:55
  • I think it's quite clear: RE2 doesn't allow you to have your same inventory and start a new playthrough, similar to what other games do with a "new game plus" mode (Borderlands, Torchlight to name a few). Instead, you completely restart the game from scratch; however, beating the game on Leon opens a new mode as Claire and vice-versa. These are called Scenario A and Scenario B (or they were in the original).
    – Tas
    Commented Jan 31, 2019 at 2:15
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Although there is no new game plus mode you can start a new game on any difficulty and any scenario with additional weapons and unlimited ammo.

These additional weapons are unlocked by meeting certain requirements, as listed below:

  • Samurai Edge (Handgun) - Complete the game in S Rank or above in Standard Difficult
  • LE 5 (Submachine Gun) - Complete the game in S Rank or above in Hardcore Difficulty
  • ATM-4 (Rocket Launcher) - Complete the Leon's story (Side A or B) in S+ Rank in Hardcore Difficulty
  • Minigun (Minigun) - Complete the Claire's story (Side A or B) in S+ Rank in Hardcore Difficulty
  • Infinite Combat Knife (Sub weapon) - Destroy all 15 Mr. Racoon figurines hidden within the game

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