ENB has some extreme functionality (for basic usage) tied to hotkeys, such as "purging" VRAM by pressing F4. Some other functions such as the fps-limiter conflict with the keybinds in a game (can't be easily rebinded) and I would prefer disabling the hotkeys entirely as my ENB build is rather minimalistic (only SSAO and SMAA) and doesn't require any configuration.
On /r/skyrimmods it's said that the hotkeys can be turned off by adding
enblocal.ini, but the file doesn't exist on my system, only
enbseries.ini does (the same method doesn't work).