Some guns in Enter the Gungeon have multiple possible synergies triggered by other items or gun. In some case these synergies enable an alternate mode for the gun.

For example, Heroine - a gun based on Samus Arran's arm cannon - has three different synergies for also possessing three specific other guns. Reloading with a full magazine when holding one of those guns enable a secondary mode for Heroine (reference on the wiki: link)

  • Ice Beam - If the player has Frost Bullets, enables Ice Beam mode, which fires a projectile that instantly freezes an enemy when fully charged.
  • Plasma Beam - If the player has Hot Lead, enables Plasma Beam mode, which fires a fire laser when uncharged and a large piercing fire projectile when charged.
  • Wave Beam - If the player has Shock Rounds, enables Wave Beam mode, which fires two wavy projectiles connected by electricity when uncharged, and a standard large Heroine shot when charged.

Megahand has a similar mechanic too, but offers even more alternate modes - eight. No surprise since the weapon is a reference to Megaman blaster.

The question is simple. Since the synergy is triggered by reloading the Heroine/Megahand gun while holding any of the three other guns... what happens if one posses more of one of those?

To put it more simply: what happens if the player qualifies for more than one of those synergy at the same time?

1 Answer 1


Based on this item showcase video on Youtube the answer is actually quite simple.

Reloading with a full ammo clip will simply allow to switch between every alternate mode currently available to the gun. So, assuming the player has Frost Bullets, Hot Lead and Shock Rounds... Heroine would just cycle between all three modes.

Heroine -> Ice Beam -> Plasma Beam -> Wave Beam -> Heroine

Cycling to a different alternate mode should not consume any additional ammo.

You must log in to answer this question.

Not the answer you're looking for? Browse other questions tagged .