I have managed to get all the achievements for the game as well as all the collectibles and all the upgrades, but it took two play-throughs to do so. I am currently replaying A Plague Tale: Innocence again to see if I can get all the collectibles and upgrades with one play-through.
In order to attempt this, I looked at a bunch of tutorials. The ones I have found all caution against doing the alchemy upgrades, because it jeopardizes the ability to upgrade the sling and equipment upgrades.
To possibly achieve this, I'd have to play thoroughly. It means that I have to be absolutely stingy with my resources and explore every corner, especially for the rare items such as leather, cloth and cord.
Has anyone managed to get all of the above in a single play-through successfully?