I've been playing Skyrim for a few months without issue -- character is level 38.
Suddenly, today, I'm getting very frequent crashes to desktop -- usually when I'm in major cities. Often just after fast travelling, but can also happen while I'm running/sprinting through town. It may not be related by my sprint function (ALT) has gotten a little sticky-glitchy today, too.
I've tried lowering various setting (shadows, anti-aliasing, etc). Seemed to help a little but not much -- or that may have been coincidence. Screen resolution is at the lowest setting. I read on other fora that sometimes the size of individual game files could be problematic, if they're near 18MB -- mine are all under 10MB (though I tried the sleep-for-7-days fix that was recommended to help that, just in case). I've read that some mods can be problematic, but I'm only running one small mod -- the one that make veils of ore glow, so you can spot them easily -- and the problem never happens when I'm out in the wilderness near ore veils, so I think it's unrelated.
Anyone? Anything? I'd be very grateful for any suggestions. Ideally couched in human-speak, rather than computer-speak ... I'm only semi-computer literate.