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Are there any important points of no return?
Are there time-limited objectives in the game?
In Mass Effect 2, there was a point where you had to abandon doing any more side missions and focus on the main story to avoid serious consequences where half or the entire crew of the Normandy dies if you wait too long to rescue them.
However, it was possible to do all side missions and still save everybody if you were careful to delay obtaining the Reaper IFF until all side missions were done.
With Earth under attack there is a clear sense of urgency in Mass Effect 3, so I'm wondering if I really have time to go cruising around the galaxy, or if this will have negative consequences in the final outcome.
In other words, if I want to do as many side missions as possible, do I have to be careful to avoid consequences?