In Skyrim (Xbox 360), I went to the Shrine of Peryite a while back, and Kesh was annoying me, so I killed him. Can I still start the quest "The Only Cure"? Or will I never be able to obtain that Daedric artifact?
"The Only Cure" article on The Elder Scrolls Wiki would suggest that it is possible to complete the quest even after killing Kesh (relevant emphasis added):
Kesh tells the Dragonborn that in order to speak to Peryite, they must:
- Obtain a silver ingot
- Obtain a deathbell flower
- Obtain some vampire dust
- Obtain a flawless ruby
- Give all of the acquired items to Kesh
- Inhale the fumes
After doing so, Peryite will appear to the Dragonborn as a spectral apparition […]
The quest can also be triggered by simply collecting the items needed (listed above) and going to the cauldron and activating it. This will start the quest.