In NCAA 11, the achievement In Your Crosshairs is described like this:
Spotlight a receiver and get an interception on him
How do I spotlight a receiver?
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How: To spotlight a receiver you will need to hold L2 and then select the corresponding button above the receiver, tight end or running back. To increase odds of getting this trophy Spotlight the other teams top player on every play. You only need to intercept the pass you do not need to return it for a TD.