According to [this post from a dev][1], in the Reign of Giants expansion, killer bees can be used for crafting during some parts of the year provided you have encountered them in the wild and not caused them to spawn from a hive.  

  [1]: http://forums.kleientertainment.com/topic/32359-killer-bees-spawning-in-place-of-bumblebees-in-spring-pollinating-flowers/?page=0#comment-430986