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I applied 6 patches or so in a row. I suspect this may has to do something with v-sync off(as many game adjust their time clock to frames as well causes some physics problems like in Skyrim). I have no time to test it right now.
And also seems killing Granny later is counted towards murder case therefore you can't get "didn't kill anyone" chapter achievement? I've killed somehow two people(though I only used choke) so can't really figure out whether granny counted towards these kills.