Consider the mission of travelling from Kerbin to Ike (low orbit). There are two ways of getting to Ike that I'm trying to compare in terms of fuel requirements.

First method: Duna capture, Ike flyby

1. Leave Kerbin and get a Duna flyby.
2. Fine-tune Duna flyby for a low Duna periapsis.
3. Burn retrograde at the Duna periapsis to achieve an elliptical orbit.
4. Wait for a good window then fly by Ike, adjusting the current orbit if needed.
5. Fine-tune Ike orbit for a periapsis at low orbit.
6. Burn retrograde at periapsis to achieve low Ike orbit.

Second method: direct Ike flyby and capture

1. Leave Kerbin and get a Duna flyby.
2. Fine-tune Duna flyby for an Ike flyby + low Ike periapsis.
3. Burn retrograde at the Ike periapsis to achieve low Ike orbit.

Which scenario requires less ΔV? Is this typical for other Kerbin -> E.T. Moon trips? Are there any corner cases or exceptions to the norm (e.g. high/low planet:moon mass ratios, Laythe, etc)?

Consider the mission of travelling from Kerbin to Ike (low orbit). There are two ways of getting to Ike that I'm trying to compare in terms of fuel requirements.

First method: Duna capture, Ike flyby

1. Leave Kerbin and get a Duna flyby.
2. Fine-tune Duna flyby for a low Duna periapsis.
3. Burn retrograde at the Duna periapsis to achieve an elliptical orbit.
4. Wait for a good window then fly by Ike, adjusting the current orbit if needed.
5. Fine-tune Ike orbit for a periapsis at low orbit.
6. Burn retrograde at periapsis to achieve low Ike orbit.

Second method: direct Ike flyby and capture

1. Leave Kerbin and get a Duna flyby.
2. Fine-tune Duna flyby for an Ike flyby + low Ike periapsis.
3. Burn retrograde at the Ike periapsis to achieve low Ike orbit.

Which scenario requires less ΔV? Is this typical for other Kerbin -> E.T. Moon trips? Are there any corner cases or exceptions to the norm (e.g. high/low planet:moon mass ratios, Laythe, high/low spacecraft eccentricity around Kerbol, etc)?