If you open the chest normally, 1d20 will be rolled. The chest will give the following based on the result of this roll:
- 1: 1 Eridium, live grenade
- 2-3: White (common) items
- 4-14: Green (uncommon) items
- 15-18: Blue (rare) items
- 19: One blue and one purple (epic) item (a rocket launcher will be purple rarity)
- 20: Purple or E-tech items
If you spend 5 Eridium, 2d20 will be rolled and the higher of the two dice will be taken as the result for determining loot quality (i.e. rolling with advantage in D&D 5e). In addition to the above, the following special cases apply:
- 1 on both dice: 4 Eridium, three live grenades
- 20 on both dice: Orange (legendary) item; possibly a pearlescent item if in UVHM
Source: Borderlands Wiki