In-game picture of Madagascar

The country of Madagascar is only reachable through sea. This means that if the country closes its shipyard before I reach it there is no way I can possibly win… or is there?

How can I work around this?


  • 16
    – Rapida
    Commented Jun 19, 2011 at 23:47
  • 1
    Great question, I could never infect Madagascar. (grrrrr)
    – Kevin Yap
    Commented Jun 20, 2011 at 4:03
  • 5
    In "realistic mode," madagascar shuts down its borders even if my disease has no symptoms and has killed 0 people. Come on. Commented Jun 20, 2011 at 7:26
  • 3
    The easiest way by far is to keep restarting the game until you start in Madagascar. :P
    – GnomeSlice
    Commented Dec 5, 2012 at 17:31
  • 1
    It's strange that if you can spread by rodent and insects you can't pass the closed border. But you can't.
    – Yaroslav
    Commented Oct 10, 2014 at 21:18

3 Answers 3


Okay, so it's been a while since I beat Pandemic 2 and got Kongregate's President Madagascar Assassin Badge, but I'll try to answer with what I remember.

Be Infectious, but not Deadly

You can alter your infectious disease at will. Because infected people never become uninfected, it's a totally valid strategy to infect as many people as possible and then mutate into a 100% mortality rate disease.

Be Infectious, but Invisible

You do have to be careful however, because even decidedly non-deadly diseases may spark airport / harbor closure, which may make Madagascar the human's best hideout. Don't go for the High Infection, High Visible symptoms, it's counteractive to your goal of INFECTING EVERY PATHETIC HUMAN ON EARTH. Remember - transmissions lead to closures!

Be a Virus

The benefits of fast mutation far outway the benefits of the other vectors.

Start in Madagascar

Or Canada, New Zealand, Cuba, Greenland, or West Europe. The point is, since these countries tend to be easiest to close, you may as well start there, to cut out on some headaches later. You can simply remake new games until you get one of these countries.

And finally, a TLDR from the Kongregate comments:

  1. Pick Virus.
  2. Start in Canada, New Zealand, Cuba, Greenland, West Europe, or Madagascar. If you do not get there restart.
  3. Sell the starting symptoms, and buy sneezing (unless it is what you started with, just keep it).
  4. Buy 1-1-1-0 resistances but no transmissions (they trigger closures).
  5. Once four countries are infected, sell sneezing to get rid of visibility.
  6. Wait until all countries are infected. If Madagascar closes its shipyards/borders or is not infected in 30 days, restart.
  7. Buy all four drug resistances AND sneezing, coughing, and vomiting.
  8. After a few days, unlock tiers 2-3, (do not buy tier 4 ever!) keeping whatever symptoms it gives you.
  9. Buy fever, fatigue, diarrhoea, pulmonary edema, and hypersensitivity. Then save for kidney failure and ataxia.
  • 1
    Any idea why you shouldn't buy Tier 4?
    – Steve V.
    Commented Jun 20, 2011 at 16:35
  • @Steve - I would guess it's not as useful as the lower tiers. Commented Jun 20, 2011 at 16:58

Generally speaking a more visible disease will make you suspectible to Madagascar closing the shipyard, the only way in, so sell all your starting symptons and be a parasite. Apparently rodents travel on boats, but when trying to get rodents to infect Madagascar they spread the disease to quickly and Madagascar's paranioa kicks in. Buy level two drug resistance, but save heat and cold resistance until at least ONE country other than your starting region is infected. When you start to spread out of your homeland by vomiting to speed spreading until five countries are in your empire of microbes. When you spread to a new country you will quickly start to infect yet more countries normally, but this strategy makes it SLOW, and when one country starts shutting down infrastructure or enforcing curfews, others will follow.

If you haven't got Madagascar by this time you are probably to late, but play for maybe another month or so after it's closed ports and see if you get Madagascar. At this stage vaccine will probably begin development, so by full level drug resistance and (maybe) vomiting. If you've almost infected everyone start killing them now. Note that sometimes vaccine doesn't work, or even makes you more lethal, but two times out of the four times vaccine has been developed in my games it works, and prevents me killing people (but that was before I evolved to be deadly). Once you've got every country bar three or four buy rodent, insect, air and finally water transmission and really ramp up your resistance. If a country has closed borders, no active air or seaports, and no water by this time and they are still not infected, forget it. Then buy symptons which increase infectivity. Once you've infected EVERYONE (take no chances), start killing people. You should have at least fifty, maybe even a hundred evolution points, so you may as well buy tier four stuff (heart and brain faliure). If you're a tad short of evolution points, buy fever, vomiting, fatigue and diarrhea, as well as stuff like hemorrhaging. This deadly cocktial should easily kill people.

When I used this strategy half the time I infect Madagascar (1st and 4th time), but on the 1st time Peru managed to escape. On the 2nd and 3rd time Madagascar escaped. But on the 4th try (started in Brazil with Mutator trait and heat resistance 1) I infected Madagascar (it wasn't last, in fact it kept the ports open for a while), then Russia and USA (you can get them after they close airports and ports, but if borders are also closed you're in trouble). I bought all transmissions and vomiting, and I infected about a billion people in a day. When I had about 8 healthy people left I bought Pulmonary Edema, Fatigue, Fever and Hypersensitivity (I had to buy Tiers 2 and 3) because the vaccine was being deployed. The vaccine worked but because I had mutated before deployment I kept killing. In about a month (it was new year) 90% of people were dead. Before March 2009 I had succeded/


It's been a while since I've played this game, but I had better luck with infections that have a less pronounced effect.

Avoid any abiltiies that say "will make an infected person noticeable."

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