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I know you can sometimes spontaneously create them when performing alchemy if you have the skills, and I'm constantly picking up lesser variants off of dead enemies. However, since mutagens are not reverseable or upgradeable once they've been applied, is there any actual use to the lesser mutagens? It would be nice, and also fit into the alchemy system if you could somehow combine lesser mutagens into higher level ones but I certainly have not seen this ability anywhere in the game?

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Nope. Lesser Mutagens do have the advantage of being very good vendor fodder for their weight (~9 orens / .1 weight ).

If you (smartly) want to wait until you have greater version of whatever mutagen you're looking for, the only use the non-greater mutagens are good for is selling them.

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  • I'll just add that the "Madness" Mutagen seems to be about as good as the "Greater" ones, but doesn't come in a lesser/greater version.
    – Damien Stark
    Commented Jun 4, 2011 at 21:51
  • @Damien - What's the Madness mutagen from? I've not seen it.
    – Raven Dreamer
    Commented Jun 4, 2011 at 21:56
  • I actually don't remember where I got it. I assume it was a random drop like the others, but I may have raided it from a chest or not noticed receiving it from a special monster rather than the random ones. See chalonverse.com/tw2db/item.php?id=4661 though...
    – Damien Stark
    Commented Jun 7, 2011 at 18:28
  • @Damien - odd... if it's just +Damage, there's already a mutagen that does that...
    – Raven Dreamer
    Commented Jun 7, 2011 at 18:31
  • it's the damage bonus, plus 2 armor and 5 vitality. Apparently a very rare random drop.
    – Damien Stark
    Commented Jun 8, 2011 at 14:07

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